Following the initial cabinet purge on 20 July 2026, Prime Minister Andy Burnham continued restructuring the government by abolishing the Department for Science, Innovation and Technology (DSIT) on 21 July 2026. This move resulted in the removal of Liz Kendall as Science Secretary, while Science Minister Patrick Vallance also resigned from the administration. The reshuffle has seen a significant number of Keir Starmer's former cabinet members replaced by Burnham loyalists as the new ministry takes shape.
- Liz Kendall removed as Science Secretary: On 21 July 2026, Liz Kendall left the government as Prime Minister Andy Burnham abolished the Department for Science, Innovation and Technology (DSIT), merging its responsibilities into the business department.
- Abolition of the Department for Science, Innovation and Technology: On 21 July 2026, the Burnham administration formally closed the dedicated science ministry (DSIT), transferring the science and innovation portfolio to the Department for Business, Innovation, Science and Trade.
- Patrick Vallance resigns as Science Minister: On 21 July 2026, it was confirmed that Patrick Vallance resigned his position as Science Minister for personal reasons amidst the wider government restructuring.
- Formalization of new Cabinet appointments: Between 21 July and 22 July 2026, the government formalized several key appointments, including Ed Miliband as Foreign Secretary, Yvette Cooper as Health Secretary, and Louise Haigh as First Secretary of State.